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MELANOTAN-1 10MG
SKU NP-MT1-10MG
$50.00
CAD
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Overview
Properties
Research
Lab Results
FAQ
Melanotan-1 overview
Melanotan-1 (Afamelanotide, MT-1, CAS# 75921-69-6) is a synthetic linear 13-amino-acid analogue of native alpha-melanocyte-stimulating hormone (α-MSH), carrying Nle⁴ and D-Phe⁽ substitutions that enhance metabolic stability and MC1R binding potency relative to the native hormone. NexPept supplies it as a lyophilized research reference standard for MC1R receptor binding assays, melanogenesis pathway studies, and in vitro photoprotection mechanism research. Not for use in any living organism.
Every lot is independently tested by a third-party analytical laboratory before it is listed. The Certificate of Analysis reports HPLC purity, mass spectrometry identity confirmation, and net-content verification, and stays published in our COA library after the batch sells out.
For background on the compound itself — what the Nle⁴ and D-Phe⁷ substitutions do, the MC1R selectivity, and the published record — see our Melanotan-1 research overview, or compare the two analogues directly in Melanotan-1 vs Melanotan-2.
✓
99.54% HPLC purity on the current lot✓
Mass spectrometry identity confirmed✓
Batch number printed on every vial✓
Certificate published, not available on requestStudied in vitro for
Batch verification
Current lot
Third-party lab verified
HPLC + mass spectrometry
BatchNP-MT1-062426-01
TestedJul 28, 2026
Purity99.54%
Properties
| CAS Number | 75921-69-6 |
|---|---|
| Full Name | Afamelanotide |
| Synonyms | MT-1; α-MSH analogue |
| Compound Class | Synthetic linear α-MSH analogue — MC1R agonist |
| Sequence Length | 13 amino acids |
| Molecular Formula | C₇₈H₁₁₁N₂₁O₁₉ |
| Molecular Weight | 1646.87 g/mol |
| Physical Form | Lyophilized powder |
| Appearance | White to off-white lyophilized solid |
| Net Quantity | 10 mg / vial |
| Analytical Method | HPLC + Mass Spectrometry |
Research context
Melanotan-1 is used as a peptide tool compound in preclinical in vitro settings. Published work has examined its behaviour in MC1R receptor binding assays, melanogenesis pathway studies, photoprotection and DNA repair-related signalling research, and anti-inflammatory pathway models in macrophage systems.
As a linear 13-amino-acid analogue with Nle⁴ and D-Phe⁽ substitutions that enhance metabolic stability and receptor binding potency relative to native α-MSH, it is used in controlled laboratory environments to study melanocortin receptor pharmacology and downstream signalling mechanisms. Melanotan-1 is catalogued under neuro research. Lot-to-lot consistency matters for this kind of work, which is why every NexPept batch is published with its own purity figure rather than a blanket claim.
This compound has not been authorized by Health Canada for any therapeutic, clinical, or human use.
Further reading
Melanotan-1 research overview — the two substitutions, MC1R selectivity and the research record
Melanotan-1 vs Melanotan-2 — side-by-side structure, receptor profile and which suits which study
Melanotan-2 research overview — the shorter, cyclic, non-selective counterpart
KPV research overview — the alpha-MSH C-terminal tripeptide, the last three residues of this sequence
What are research peptides? — how research-grade material differs from a drug or a supplement
Buy peptides in Canada — sourcing, documentation and what to check before ordering
PubMed — Melanotan-1 / Afamelanotide — peer-reviewed scientific literature
NexPept COA Library — published certificates for every batch we have sold
Lab results
Certificates for the lots we have shipped. The batch number on your vial matches one of these.
Research Use Only. All products are intended solely for laboratory research use and are not for human or veterinary use. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Frequently asked questions
What testing does each batch go through?
Identity and purity are confirmed by high-performance liquid chromatography and mass spectrometry before a lot is listed. The current lot, NP-MT1-062426-01, tested at 99.54% on July 28, 2026. If a lot has not been tested, it does not go on sale.
What class of compound is Melanotan-1?
A synthetic linear 13-amino-acid analogue of native alpha-melanocyte-stimulating hormone (α-MSH), carrying Nle⁴ and D-Phe⁽ substitutions. Supplied as a lyophilized powder and handled as a peptide reference standard, not as a formulation.
How does Melanotan-1 differ from Melanotan-2?
Melanotan-1 is a linear 13-amino-acid sequence, while Melanotan-2 is a shorter cyclic analogue with a different receptor selectivity profile. Researchers select between the two depending on whether their model calls for the linear or cyclic scaffold — our Melanotan-1 vs Melanotan-2 comparison sets the sequences, receptor profiles and research applications side by side, and Melanotan-2 10mg is listed separately.
What physical form does it arrive in?
A white to off-white lyophilized (freeze-dried) solid, sealed in a single vial. Net quantity is 10mg. No preparation, reconstitution or handling instructions are supplied; those are determined by qualified personnel under your own institutional protocols.
All products are intended for laboratory research use only. Not for human or veterinary use.
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Frequently Asked Questions
Everything you need to know before ordering
Product Quality Summary is available on every product page. Independent third-party Certificates of Analysis are available upon request for select batches and may be verified directly with the testing laboratory.
Please note that all sales are final. Due to the nature of our products and inventory, we are unable to accept returns. Product quality is independently assessed via 3rd party laboratory testing to ensure quality, and all purchases made via this website are done with the implied consent that you acknowledge and accept the empirical testing provided on each product page. In the event of dissatisfaction or quality concern, please consult with us via email so that we can try to assist.
We ship to addresses within Canada only. All orders are shipped domestically via Xpress Post with Canada Post to ensure safe, discreet delivery.
Most orders ship the same business day. Orders within the Greater Toronto Area (GTA) typically arrive within 1–2 business days, while more rural or remote areas can expect 3–5 business days. FlexDelivery and PO Boxes are supported. Please note these are average delivery times — delays may occasionally occur due to courier issues or remote locations.
Every peptide product sold on our site is lab-tested before it's listed. If a product hasn't been tested, we don't sell it.
Unless otherwise noted on the product page, all NexPept research compounds are supplied as lyophilized (freeze-dried) powder for laboratory research use. Physical form and net quantity are listed individually on each product page.