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TB-500 10mg
SKU NP-TB500-10MG
$65.00
CAD
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Overview
Properties
Research
Lab Results
FAQ
TB-500 10mg overview
TB-500 (Thymosin Beta-4 fragment, CAS# 77591-33-4) is a synthetic 43-amino-acid actin-regulatory peptide built around the LKKTET motif, the minimal actin-binding sequence in the native protein. NexPept supplies it as a lyophilized research reference standard for cytoskeletal signalling and cell migration studies. Not for use in any living organism.
Every lot is independently tested by a third-party analytical laboratory before it is listed. The Certificate of Analysis reports HPLC purity, mass spectrometry identity confirmation, and net-content verification, and stays published in our COA library after the batch sells out.
For background on the compound itself — actin sequestration, the LKKTET motif and the published record — see our TB-500 research overview, or compare it against related compounds in GHK-Cu vs TB-500 and BPC-157 vs TB-500.
✓
99.34% HPLC purity on the current lot✓
Mass spectrometry identity confirmed✓
Batch number printed on every vial✓
Certificate published, not available on requestStudied in vitro for
Batch verification
Current lot
Third-party lab verified
HPLC + mass spectrometry
BatchTB500-10MG-B01
TestedMay 8, 2026
Purity99.34%
Properties
| CAS Number | 77591-33-4 |
|---|---|
| Full Name | Thymosin Beta-4 |
| Synonyms | Tβ4 |
| Compound Class | Synthetic actin-regulatory peptide |
| Sequence Length | 43 amino acids |
| Molecular Formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molecular Weight | 4963.44 g/mol |
| Physical Form | Lyophilized powder |
| Appearance | White to off-white lyophilized solid |
| Net Quantity | 10 mg / vial |
| Analytical Method | HPLC + Mass Spectrometry |
Research context
TB-500 is used as a peptide tool compound in preclinical in vitro settings. Published work has examined its behaviour in G-actin sequestration and cytoskeletal dynamics research, cell migration assays including scratch and transwell models, in vitro angiogenesis pathway studies involving endothelial cells, and ILK/integrin signalling investigations examining AKT and GSK-3β interactions.
As a defined 43-amino-acid sequence with consistent structural characteristics between lots, it is used in controlled laboratory environments to study actin-binding kinetics and downstream cytoskeletal signalling mechanisms. TB-500 is catalogued under cellular research. Lot-to-lot consistency matters for this kind of work, which is why every NexPept batch is published with its own purity figure rather than a blanket claim.
This compound has not been authorized by Health Canada for any therapeutic, clinical, or human use.
Further reading
TB-500 Research Peptide Overview — NexPept compound overview and in vitro research context
GHK-Cu vs TB-500 — a copper complex acting outside cells against an actin-binding peptide acting inside them
BPC-157 vs TB-500 — the closer comparison, side by side
Healing Blend overview — the combined BPC-157 and TB-500 format
What are research peptides? — how research-grade material differs from a drug or a supplement
Buy peptides in Canada — sourcing, documentation and what to check before ordering
PubMed — thymosin beta-4 / TB-500 — peer-reviewed scientific literature
NexPept COA Library — published certificates for every batch we have sold
Lab results
Certificates for the lots we have shipped. The batch number on your vial matches one of these.
Research Use Only. All products are intended solely for laboratory research use and are not for human or veterinary use. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Frequently asked questions
What testing does each batch go through?
Identity and purity are confirmed by high-performance liquid chromatography and mass spectrometry before a lot is listed. The current lot, TB500-10MG-B01, tested at 99.34% on May 8, 2026. If a lot has not been tested, it does not go on sale.
What class of compound is TB-500?
A synthetic 43-amino-acid actin-regulatory peptide fragment of Thymosin Beta-4, built around the LKKTET motif. It is supplied as a lyophilized powder and handled as a peptide reference standard, not as a formulation.
How does the BPC-157 / TB-500 blend differ from TB-500 alone?
The blend vial contains 5mg of each compound rather than 10mg of one. Researchers running comparative work on the two sequences usually take the single-compound vials — this one and BPC-157 10mg — so each can be varied independently; the blend is a convenience format at a fixed ratio.
What physical form does it arrive in?
A white to off-white lyophilized (freeze-dried) solid, sealed in a single vial. Net quantity is 10mg. No preparation, reconstitution or handling instructions are supplied; those are determined by qualified personnel under your own institutional protocols.
All products are intended for laboratory research use only. Not for human or veterinary use.
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Frequently Asked Questions
Everything you need to know before ordering
Product Quality Summary is available on every product page. Independent third-party Certificates of Analysis are available upon request for select batches and may be verified directly with the testing laboratory.
Please note that all sales are final. Due to the nature of our products and inventory, we are unable to accept returns. Product quality is independently assessed via 3rd party laboratory testing to ensure quality, and all purchases made via this website are done with the implied consent that you acknowledge and accept the empirical testing provided on each product page. In the event of dissatisfaction or quality concern, please consult with us via email so that we can try to assist.
We ship to addresses within Canada only. All orders are shipped domestically via Xpress Post with Canada Post to ensure safe, discreet delivery.
Most orders ship the same business day. Orders within the Greater Toronto Area (GTA) typically arrive within 1–2 business days, while more rural or remote areas can expect 3–5 business days. FlexDelivery and PO Boxes are supported. Please note these are average delivery times — delays may occasionally occur due to courier issues or remote locations.
Every peptide product sold on our site is lab-tested before it's listed. If a product hasn't been tested, we don't sell it.
Unless otherwise noted on the product page, all NexPept research compounds are supplied as lyophilized (freeze-dried) powder for laboratory research use. Physical form and net quantity are listed individually on each product page.