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MOTS-C 40mg
SKU NP-MOTSC-40MG
$120.00
CAD
10mg40mg
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Overview
Properties
Research
Lab Results
FAQ
MOTS-C 40mg overview
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c, CAS# 1627580-64-6) is a synthetic 16-amino-acid mitochondria-derived peptide (MDP) encoded within the 12S rRNA gene of mitochondrial DNA. NexPept supplies it as a lyophilized research reference standard for AMPK-pathway signaling assays, mitochondria-to-nucleus retrograde signaling studies, and metabolic-regulation research in cell-based models. Not for use in any living organism.
Every lot is independently tested by a third-party analytical laboratory before it is listed. The Certificate of Analysis reports HPLC purity, mass spectrometry identity confirmation, and net-content verification, and stays published in our COA library after the batch sells out.
For background on the compound itself — why it is encoded in mitochondrial DNA rather than the nucleus, and what the published research record covers — see our MOTS-c research overview.
✓
99.91% HPLC purity on the current lot✓
Mass spectrometry identity confirmed✓
Batch number printed on every vial✓
Certificate published, not available on requestStudied in vitro for
Batch verification
Current lot
Third-party lab verified
HPLC + mass spectrometry
BatchNP-MOTSC-02
TestedAug 28, 2026
Purity99.91%
Properties
| CAS Number | 1627580-64-6 |
|---|---|
| Full Name | Mitochondrial Open Reading Frame of the 12S rRNA-c |
| Compound Class | Synthetic mitochondria-derived peptide (MDP) |
| Sequence Length | 16 amino acids |
| Molecular Formula | C₁₀₁H₁₅₂N₂₈O₂₂S₂ |
| Molecular Weight | 2174.62 g/mol |
| Physical Form | Lyophilized powder |
| Appearance | White to off-white lyophilized solid |
| Net Quantity | 40 mg / vial |
| Analytical Method | HPLC + Mass Spectrometry |
Research context
MOTS-c is used as a peptide tool compound in preclinical in vitro settings. Published work has examined its role in AMPK-pathway activation, mitochondria-to-nucleus retrograde signaling, folate-cycle interactions, and insulin-signaling/glucose-metabolism cell models.
As a defined 16-amino-acid sequence encoded within mitochondrial DNA, it is used in controlled laboratory environments to study mitochondrial-nuclear communication and downstream metabolic signaling. Lot-to-lot consistency matters for this kind of work, which is why every NexPept batch is published with its own purity figure rather than a blanket claim.
This compound has not been authorized by Health Canada for any therapeutic, clinical, or human use.
Further reading
MOTS-c research overview — mitochondrial-derived peptides, reported mechanisms and the research record
What are research peptides? — how research-grade material differs from a drug or a supplement
Buy peptides in Canada — sourcing, documentation and what to check before ordering
PubMed — MOTS-c — peer-reviewed scientific literature
NexPept COA Library — published certificates for every batch we have sold
Lab results
Certificates for the lots we have shipped. The batch number on your vial matches one of these.
Research Use Only. All products are intended solely for laboratory research use and are not for human or veterinary use. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Frequently asked questions
What testing does each batch go through?
Identity and purity are confirmed by high-performance liquid chromatography and mass spectrometry before a lot is listed. The current lot, NP-MOTSC-02, tested at 99.91% on August 28, 2026. If a lot has not been tested, it does not go on sale.
What class of compound is MOTS-c?
A synthetic mitochondria-derived peptide (MDP) — a 16-amino-acid sequence encoded within the 12S rRNA gene of mitochondrial DNA. It is supplied as a lyophilized powder and handled as a peptide reference standard, not as a formulation.
How does the 40mg vial differ from the 10mg vial?
Both vials contain the same MOTS-c sequence at the same purity standard — the only difference is net content per vial. Labs running smaller pilot assays or single-plate studies often take the 10mg vial instead to avoid excess unused material.
What physical form does it arrive in?
A white to off-white lyophilized (freeze-dried) solid, sealed in a single vial. Net quantity is 40mg. No preparation, reconstitution or handling instructions are supplied; those are determined by qualified personnel under your own institutional protocols.
All products are intended for laboratory research use only. Not for human or veterinary use.
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Frequently Asked Questions
Everything you need to know before ordering
Product Quality Summary is available on every product page. Independent third-party Certificates of Analysis are available upon request for select batches and may be verified directly with the testing laboratory.
Please note that all sales are final. Due to the nature of our products and inventory, we are unable to accept returns. Product quality is independently assessed via 3rd party laboratory testing to ensure quality, and all purchases made via this website are done with the implied consent that you acknowledge and accept the empirical testing provided on each product page. In the event of dissatisfaction or quality concern, please consult with us via email so that we can try to assist.
We ship to addresses within Canada only. All orders are shipped domestically via Xpress Post with Canada Post to ensure safe, discreet delivery.
Most orders ship the same business day. Orders within the Greater Toronto Area (GTA) typically arrive within 1–2 business days, while more rural or remote areas can expect 3–5 business days. FlexDelivery and PO Boxes are supported. Please note these are average delivery times — delays may occasionally occur due to courier issues or remote locations.
Every peptide product sold on our site is lab-tested before it's listed. If a product hasn't been tested, we don't sell it.
Unless otherwise noted on the product page, all NexPept research compounds are supplied as lyophilized (freeze-dried) powder for laboratory research use. Physical form and net quantity are listed individually on each product page.